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Molecular Weight: 731
is a Retinoic acid receptor agonist (RAR)
In primary human bronchial epithelial (HBE) cells with F508del-CFTR mutation
1262036-50-9
Molecular Weight: 1058
NVP-BKM120 Hydrochloride - CAS# 1312445-63-8 Catalog No.:M10296-2 Molecular Weight: 731Buparlisib, also known as BKM120, is an orally bioavailable specific oral inhibitor of the pan class I phosphatidylinositol 3 kinase (PI3K) family of lipid kinases with potential antineoplastic activity. PI3K inhibitor BKM120 specifically inhibits class I PIK3 in the PI3K AKT kinase (or protein kinase B) signaling pathway in an ATP competitive manner, thereby inhibiting the production of the secondary messenger phosphatidylinositol 3,4,5 trisphosphate