DDR1-IN-1 dihydrochloride ole sulfone A selective inhibitor of PRMT5

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

which inhibits the formation of the glycosaminoglycan-amyloid fibril aggregate

BMS-186295 D4

(S)-(-)-Verapamil hydrochloride

GSK2879552 was used at 1 µM in vitro and cellular assays

DDR1-IN-1 dihydrochloride ole sulfone A selective inhibitor of PRMT5DDR1 IN 1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4 fold less potent for DDR2 (IC50 = 413 nM). Product information CAS Number: 1780303 76 5 Molecular Weight: 625. 51 Formula: C30H33Cl2F3N4O3 Chemical Name: 4 [(4 ethylpiperazin 1 yl)methyl] N {4 methyl 3 [(2 oxo 2,3 dihydro 1H indol 5 yl)oxy]phenyl} 3 (trifluoromethyl)benzamide dihydrochloride Smiles: Cl. Cl.