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1 mg/kg) has excellent PK characteristics with 76% bioavailability
Mal-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
Naratriptan is a selective 5-HT1 receptor subtype agonist for the treatment of migraine headache
and also induces Her-2 degradation
CDK9 inhibitor is a 4-aminophenyl derivative based on the (6-phenyl-pyrimidin-4-yl)-phenylamine structure
Lenalidomide-acetylene-C5-COOH 196moxiterol 1 mg/kg) has excellent PKLenalidomide acetylene C5 COOH (compound 43; Cereblon ligand linker Conjugate) is the Lenalidomide based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide acetylene C5 COOH can be connected to the ligand for protein by a linker to form PROTAC. Product information CAS Number: 2429878 72 6 Molecular Weight: 382. 41 Formula: C21H22N2O5 Chemical Name: 8 [2 (2,6 dioxopiperidin 3 yl) 1 oxo 2,3 dihydro 1H isoindol 4 yl]oct 7 ynoic acid
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