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D609 - CAS# 83373-60-8 tin-3'-sulfonate InChi: InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H

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Description

InChi: InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H

CAS Number: 121123-17-9

Smiles: C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2[C@H](O)C[C@]2(C)[C@H](CC[C@@]21O)C1C=CC(=O)OC=1

CAS Number: 2315-02-8

GDC-0349 was orally dosed to mice at 30-80 mg/kg once per day

D609 - CAS# 83373-60-8 tin-3'-sulfonate InChi: InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8HD 609, also known as D 609 free, is a phospholipase C inhibitor potentially for the treatment of pancreatic cancer. D 609, an inhibitor of PC PLC and sphingomyelin synthase, strongly inhibited myogenic tone and had no effect on depolarization induced contraction. D 609 appeared to act by lowering cytoplasmic Ca(2+) concentration to levels below those that activate contraction. Product information CAS Number: 83373 60 8 Molecular Weight: 266. 46

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