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specifically at 305 μM
It inhibits KDM2A at IC50 ~1
2011 Jan 19
resulting in hemorrhagic necrosis and a decrease in angiogenesis
Clotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections
RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 specifically at 305 μMRX 3117, also known as TV 1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX 3117 is taken up by cells through a carrier mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX DP) and triphosphate forms (RX TP). The triphosphate form is incorporated into
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