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The overall selectivity of LX7101 for LIMK2 increases at the higher physiological ATP concentrations
PubMed PMID: 26898815
including the ten cell lines that are sensitive to the growth inhibitory activity of Compound D
InChiKey: PRMWGUBFXWROHD-UHFFFAOYSA-N
Smiles: CC1=C(/C=C2/C3=CC(F)=CC=C3NC/2=O)NC(C)=C1C(=O)NCCN1CCCC1
H3B-6527 Size:Contact [email protected] for quotation The overall selectivity of LX7101H3B 6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1. 2 nM and at least 250 fold selectivity over FGFR1 3 (IC50 values of 320, 1,290 and 1,060 nM respectively). Product information CAS Number: 1702259 66 2 Molecular Weight: 629. 54 Formula: C29H34Cl2N8O4 Chemical Name: N {2 [(6 {[(2,6 dichloro 3,5 dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin 4 yl)amino] 5 (4 ethylpiperazin 1 yl)phenyl}prop 2 enamide Smiles:
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