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HI/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19
2013 Aug 15
InChiKey: LIRYPHYGHXZJBZ-UHFFFAOYSA-N
Muranaka Y
Chemical Name: 1-{6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3
FIT-039 Catalog No.:M25031-C HI/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19FIT 039 is a selective, ATP competitive and orally active CDK9 inhibitor with an IC50 of 5. 8 M for CKD9 cyclin T1. FIT 039 does not inhibit other CDKs and other kinases. FIT 039 inhibits replication of HSV 1 (IC50 of 0. 69 M), HSV 2, human adenovirus, and human CMV. FIT 039 is a promising antiviral agent for inhibiting drug resistant HSVs and other DNA viruses. Product information CAS Number: 1113044 49 7 Molecular Weight: 315. 41 Formula: C17H18FN3S
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