Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 Incubation of exponentially growing RaH3

Incubation of exponentially growing RaH3 and RaH5 with 1 μM canertinib accumulated the cells in the G1-phase of the cell cycle within 24 h of treatment without induction of apoptosis

regulating deubiquitination activity of USP10 and USP13 by Beclin1 provides a mechanism for Beclin1 to control the levels of p53

17328-16-4

E-7449 shows no obvious inhibiotry effects on PARP3 or PARPs 6-16

CAS Number: 936890-98-1

Su-11274 - CAS# 658084-23-2 Catalog No.:M6418-10 Incubation of exponentially growing RaH3Su 11274, CAS No. 658084 23 2, is a selective Met tyrosine kinase inhibitor with IC50 of 10 nM. Su 11274 increases tumorigenicity and enriched for melanoma initiating cells by bioenergetic modulation. Su 11274 suppresses proliferation and motility of pancreatic cancer cells. Su 11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation. Su 11274 exhibits a selective inhibition pattern toward different receptor mutated