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MK-5108 specifically inhibited Aurora-A kinase in a panel of protein kinase assays
51(11):669-75
Alexander V
In an assay of neurotrophic activity
Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen
Cathepsin S inhibitor 801653 dihydrochloride MK-5108 specifically inhibited Aurora-A kinaseLY3000328 is a Cathepsin S inhibitor with excellent in vitro potency and selectivity against other cysteine proteases. LY3000328 is currently in clinical trials. Cathepsin S (Cat S) plays an important role in many pathological conditions, including abdominal aortic aneurysm (AAA). Inhibition of Cat S may provide a new treatment for AAA. Product information CAS Number: 1373215 15 6 Molecular Weight: 484. 52 Formula: C25H29FN4O5 Chemical Name: (3R,4S) 4
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