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Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 0012 In relevant biological assays

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Description

In relevant biological assays

The invasion and mobile abilities of OS cells are also markedly suppressed by apcin treatment

and MDA-MB436 ER negative breast cancer cells

After 24 h

425613-09-8

Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 0012 In relevant biological assaysBisindolylmaleimide I (GF109203X), a potent and highly selective PCK inhibitor., CAS No. 133052 90 1, is a potent and highly selective PCK inhibitor. bisindolylmaleimide I(GF 109203X )inhibits PKC isozymes alpha, beta 1, beta 2, gamma, delta and epsilon in vitro . GF 109203X inhibited GSK 3 in vitro, when assayed either in cell lysates (IC(50) 360 nM or in GSK 3beta immunoprecipitates (IC(50) 170 nM derived from rat epididymal adipocytes. Pretreatment

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