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Derazantinib inhibits FGFR1-4 but no other receptor tyrosine kinases in cell-free kinase assay
Smiles: COC1=CC(O)=CC(O)=C1C(=O)/C=C/C1C=CC=CC=1
63 proteases
Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics
9(3):147-53
Cucurbitacin IIb - CAS# 50298-90-3 Catalog No.:M12653-10 Derazantinib inhibits FGFR1-4 but noCucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1 2, enhances the phosphorylation of IB and NF B (p65), blocks nuclear translocation of NF B (p65) and decreases mRNA levels of IB and TNF . Product information CAS Number: 50298 90 3 Molecular Weight: 520. 70 Formula: C30H48O7 Chemical Name: (1R, 2R, 3aS, 3bS, 7S,
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