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DBeQ was shown to inhibit the ATPase activity of Vps4 with an IC50 of about 11
Completo G
Flubendazole is a microtuble polymerization inhibitor
A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene
InChi: InChI=1S/C63H98O29/c1-26-46-47(88-51-43(76)38(71)30(67)22-81-51)45(78)53(84-26)90-48-39(72)31(68)23-82-54(48)92-56(79)63-15-13-57(2
Tamibarotene - CAS# 94497-51-5 Catalog No.:M10640-10 DBeQ was shown to inhibitTamibarotene, also known as SY 1425, is an orally active, synthetic retinoid, developed to overcome all trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. As a specific retinoic acid receptor (RAR) alpha beta agonist, tamibarotene is approximately ten times more potent than ATRA in inducing cell differentiation and apoptosis in HL 60 (human promyelocytic leukemia) cell lines in vitro. Due to a lower affinity for cellular
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