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ClH/c15-7-3-4-10-8(6-7)11-12(20-10)14(19)18-13(17-11)9-2-1-5-16-9
CAS Number: 1784253-05-9
7-dihydroxy-6-methyl-3
Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
Azido-PEG6-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
AC-4-130 Catalog No.:M31939-C ClH/c15-7-3-4-10-8(6-7)11-12(20-10)14(19)18-13(17-11)9-2-1-5-16-9AC 4 130 is a potent STAT5 SH2 domain inhibitor. AC 4 130 directly binds to STAT5 and disrupts STAT5 activation, dimerization, nuclear translocation, and STAT5 dependent gene transcription. AC 4 130 induces cell cycle arrest and apoptosis in FLT3 ITD driven leukemic cells. AC 4 130 has anti cancer activity and can efficiently block pathological levels of STAT5 activity in acute myeloid leukemia (AML). Product information CAS Number: 1834571 82 2