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AS-1763 Catalog No.:M33531-C Solubility: DMSO : 100 mg/mL

SKU: 24400489267

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Description

Solubility: DMSO : 100 mg/mL (104

and improve liver fibrosis

22)16(11)14/h1-3

7 μM) induces apoptotic cell death of human umbilical vein endothelial cells (HUVEC)

Chemical Name: 3-amino-N-[(2S)-2-hydroxypropyl]-5-[4-(trifluoromethoxy)benzenesulfonyl]pyridine-2-carboxamide

AS-1763 Catalog No.:M33531-C Solubility: DMSO : 100 mg/mLAS 1763 is a Potent, Selective, Noncovalent, and Orally Available Inhibitor of Brutons Tyrosine Kinase (BTK; IC50=0. 85 nM). With significant efficacies in vivo tumor xenograft models, AS 1763 has advanced to phase 1 clinical trials. AS 1763 is a potent, selective, noncovalent, and orally available inhibitor of Brutons tyrosine kinase (IC50 = 0. 85 nM). Product information CAS Number: 2227211 00 7 Molecular Weight: 578. 64 Formula: C33H31FN6O3

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