K-252a - CAS# 99533-80-9 60261 NC[C@H]1OB(O)C2=C1C=CC=C2OCCCO

NC[C@H]1OB(O)C2=C1C=CC=C2OCCCO

Smiles: CN1C(C=CC(=O)C2=CC(F)=CC=C2)=CC=C1C=CC(=O)NO

Dovitinib significantly reduces the basal phosphorylation levels of FGFR-1

Administered subcutaneously at 200 mpk twice daily (BID)

InChi: InChI=1S/C10H11F3N2O5

K-252a - CAS# 99533-80-9 60261 NC[C@H]1OB(O)C2=C1C=CC=C2OCCCOK 252a, CAS No. 99533 80 9, also known as SF 2370, is an alkaloid isolated from Nocardiopisis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1. 8 and 1. 7 nmol L, respectively). At higher concentrations it is also an efficient inhibitor of serine threonine protein kinases (IC50 of 10 to 30 nmol L). Product information CAS Number: 99533 80 9 Molecular Weight: 467. 47