Boros uncommon gives +2/+2 until end of turn at a reasonable price of one mana, or it provides an expensive Lightning Helix, which will usually kill an opposing creature and help offset some damage with the lifegain
Similarly, Fraying Sanity milling twice the amount of cards on the enchanted player means that even a smaller mill spell can spiral out of control
Making all of your creatures replace themselves buries your opponents in card advantage and makes it hard for them to interact with your board
Fear of Missing Out and Charming Scoundrel pair with Carnage well as both discard outlets and bodies to bring back, and Collector's Vault is always available for desperation looting
It creates an incredible tension in a Commander pod after it sets everyones life to one, takes out every card in play and in hand, and leaves everyone scrambling to find a quick combination of lands and creatures
While the twin realities of Lorwyn and Shadowmoor used to alternate every 300 years, they've now fused together