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PF-543 hydrochloride - CAS# 1706522-79-3 hospho-D-Serine and both of them significantly

SKU: 36266769794

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Description

and both of them significantly decrease invasion

PF-543 hydrochloride - CAS# 1706522-79-3 hospho-D-Serine and both of them significantlyPF 543 hydrochloride (Sphingosine Kinase 1 Inhibitor II hydrochloride) is a potent, selective, reversible and sphingosine competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3. 6 nM. PF 543 hydrochloride is >100 fold selectivity for SPHK1 over SPHK2. PF 543 hydrochloride is an effective potent inhibitor of sphingosine 1 phosphate (S1P) formation in whole blood with an IC50 of 26. 7 nM. PF 543 hydrochloride induces apoptosis, necrosis, and

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